Remote Ischemic Preconditioning in High-risk Cardiovascular Surgery Patients: A Randomized-controlled Trial Nicole S. Coverdale, PhD, Andrew Hamilton,

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Remote Ischemic Preconditioning in High-risk Cardiovascular Surgery Patients: A Randomized-controlled Trial Nicole S. Coverdale, PhD, Andrew Hamilton, MD, Dimitri Petsikas, MD, R. Scott McClure, MSc, MD, Paul Malik, MD, Brian Milne, MD, Tarit Saha, MD, David Zelt, MD, Peter Brown, MD, Darrin M. Payne, MSc, MD Seminars in Thoracic and Cardiovascular Surgery Volume 30, Issue 1, Pages 26-33 (March 2018) DOI: 10.1053/j.semtcvs.2017.09.001 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Consolidated Standards of Reporting Trials diagram. Seminars in Thoracic and Cardiovascular Surgery 2018 30, 26-33DOI: (10.1053/j.semtcvs.2017.09.001) Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 2 Subgroup relative risk of the composite outcome for RIPC vs control. Seminars in Thoracic and Cardiovascular Surgery 2018 30, 26-33DOI: (10.1053/j.semtcvs.2017.09.001) Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 3 Troponin-I values 6 hours after surgery and on postoperative days 1 and 2. Dots represent values that were greater than 90% of the data. The minimal detectable value for this assay was 0.01 ng/mL. (A) All participants. (B) Cardiac surgery only. (C) Vascular surgery only. POD, postoperative day. (Color version of figure is available online.) Seminars in Thoracic and Cardiovascular Surgery 2018 30, 26-33DOI: (10.1053/j.semtcvs.2017.09.001) Copyright © 2017 Elsevier Inc. Terms and Conditions

Troponin-I values 6 hours after vascular surgery and on postoperative days 1 and 2. Seminars in Thoracic and Cardiovascular Surgery 2018 30, 26-33DOI: (10.1053/j.semtcvs.2017.09.001) Copyright © 2017 Elsevier Inc. Terms and Conditions