Advancing Acute Coronary Syndrome Assessment:

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Presentation transcript:

Advancing Acute Coronary Syndrome Assessment:

Goals

ED Visits - United States

Approach to Evaluation

Temporal Rise and Fall of Existing Necrosis Biomarkers

What is a Great Troponin Assay?

Making it More Sensitive The New Era of Troponin Use

Early Diagnosis of Myocardial Infarction With Sensitive Cardiac Troponin Assays

Rapid Exclusion of Acute Myocardial Infarction in Patients With Undetectable Troponin Using a High-sensitivity Assay

Increasingly Sensitive Assays for Cardiac Troponins A Review

Noise vs Signal The Clinical Implications of an Increasingly Sensitive Troponin Assay for Patients With Suspected Acute Coronary Syndrome

Utility of Absolute and Relative Changes in Cardiac Troponin Concentrations in the Early Diagnosis of Acute Myocardial Infarction

TRAPID-AMI Results Presented at ESC 2014

Validation of High-sensitivity Troponin I in a 2-hour Diagnostic Strategy to Assess 30-day Outcomes in Emergency Department Patients With Possible Acute Coronary Syndrome

Algorithm - Admit or Discharge

Relative Differences in Serial Troponin Measurement

Absolute Differences in Serial Troponin Measurement

Incremental Value of Copeptin for Rapid Rule Out of Acute Myocardial Infarction

Summary

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)