Navigating the mini-maze: Systematic review of the first results and progress of minimally-invasive surgery in the treatment of atrial fibrillation Sébastien.

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Navigating the mini-maze: Systematic review of the first results and progress of minimally-invasive surgery in the treatment of atrial fibrillation Sébastien P.J. Krul, Antoine H.G. Driessen, Aeilko H. Zwinderman, Wim J. van Boven, Arthur A.M. Wilde, Jacques M.T. de Bakker, Joris R. de Groot International Journal of Cardiology Volume 166, Issue 1, Pages 132-140 (June 2013) DOI: 10.1016/j.ijcard.2011.10.011 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 This figure shows four forest plots representing the proportion of the patients in sinus rhythm at 6months and 12months. The top left plot shows the results at 6months without AAD (n=7 studies) and the top right at 6months with AAD (n=6 studies). The bottom left plot shows the results at 12months without AAD (n=6 studies) and the bottom right with AAD (n=7 studies). Note that the 6months results are mostly results from studies of Edgerton et al. AAD: antiarrhythmic drugs. International Journal of Cardiology 2013 166, 132-140DOI: (10.1016/j.ijcard.2011.10.011) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 This figure shows four forest plots representing the proportion of the patients in sinus rhythm at 6months and 12months specified to the different types of AF. The forest plot at the top show the results at 6months of paroxysmal AF (n=6 studies) and persistent AF (n=6 studies).The bottom plots show the results at 12months of paroxysmal AF (n=9 studies) and persistent AF (n=8 studies) Of the studies marked with an asterisk (*) only results with the use of antiarrhythmic drugs are available. AF; atrial fibrillation. International Journal of Cardiology 2013 166, 132-140DOI: (10.1016/j.ijcard.2011.10.011) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Overall freedom from atrial fibrillation curve for minimally-invasive surgery. This figure shows the overall freedom of AF curve for minimally-invasive surgery using the reported proportions in the published papers at 6months and 12months. The blue line represents the overall results with AAD. The blue dotted line is the confidence interval of the overall results. Blue circles () represent the different studies and their outcome. Red lines and diamonds () represent results without AAD. AAD: antiarrhythmic drugs, AF: atrial fibrillation. International Journal of Cardiology 2013 166, 132-140DOI: (10.1016/j.ijcard.2011.10.011) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions