Chromatin: Nucleosome assembly during DNA replication

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Chromatin: Nucleosome assembly during DNA replication Torsten Krude Current Biology Volume 5, Issue 11, Pages 1232-1234 (November 1995) DOI: 10.1016/S0960-9822(95)00245-4

Figure 1 The principle chromatin assembly reactions during DNA replication. Reaction (a): parental nucleosomes are partially disrupted during DNA replication and the histones are directly transferred to the replicated DNA, reassembling into nucleosomes. Reaction (b): the assembly of new nucleosomes from newly synthesized and soluble histones is mediated by a chromatin assembly factor. Current Biology 1995 5, 1232-1234DOI: (10.1016/S0960-9822(95)00245-4)

Figure 2 Summary of current data on the involvement of CAF-1 in the assembly of nucleosomes during DNA replication. See text for details. Current Biology 1995 5, 1232-1234DOI: (10.1016/S0960-9822(95)00245-4)