Volume 140, Issue 2, Pages (January 2010)

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Volume 140, Issue 2, Pages 176-178 (January 2010) Forever Young Leonard Guarente Cell Volume 140, Issue 2, Pages 176-178 (January 2010) DOI: 10.1016/j.cell.2010.01.015 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Keeping Daughters Youthful Depicted is the retrograde flow of damaged protein aggregates along actin cables from the daughter bud to the mother cell during budding in yeast. CCT and Sir2p fold actin to provide the substrate for cable formation. Myo2p transports material into the bud for growth. Hsp104 binds to damaged protein aggregates to ensure their retrograde transport out of buds along actin cables. Cell 2010 140, 176-178DOI: (10.1016/j.cell.2010.01.015) Copyright © 2010 Elsevier Inc. Terms and Conditions