From Polyuria to Renal Mass: An Unexpected Link

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From Polyuria to Renal Mass: An Unexpected Link Frédéric Vandergheynst, MD, Paraskevi Kazakou, MD, PhD, Bruno Couturier, MD, Nicolas Dumarey, MD, Rose Ghanooni, MD, Agnieszka Pozdzik, MD, PhD, Sandrine Rorive, MD, PhD, Daniel Van Gansbeke, MD, Agnès Burniat, MD, PhD  The American Journal of Medicine  Volume 128, Issue 10, Pages e15-e18 (October 2015) DOI: 10.1016/j.amjmed.2015.05.009 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Pituitary magnetic resonance imaging study. (A) Gadolinium-enhanced coronal T1-weighted image (March 2014). Slightly enlarged pituitary gland (12.8 mm; solid arrow) and thickened stalk (3.9 mm; dotted arrow). (B) Sagittal T1-weighted image (March 2014). Loss of the normal hyperintense signal of the posterior pituitary (solid arrow). (C) Gadolinium-enhanced coronal T1-weighted image (March 2015). Normalization of pituitary size (solid arrow) and stalk width (dotted arrow). (D) Sagittal T1-weighted image (March 2015). Persistent loss of the normal posterior lobe T1 hyperintensity (solid arrow). The American Journal of Medicine 2015 128, e15-e18DOI: (10.1016/j.amjmed.2015.05.009) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 [18F]-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). (A) Hypermetabolic lesion in the right kidney (March 2014). (B) Expansion of the lesion in the right kidney and appearance of new lesions in the left kidney (September 2014). The American Journal of Medicine 2015 128, e15-e18DOI: (10.1016/j.amjmed.2015.05.009) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 3 Histopathological examination of the renal biopsy specimen revealed granulomatous inflammation with multinucleated giant cells, extra-capillary proliferation and fibrinoid necrosis which confirmed the diagnosis of granulomatosis with polyangiitis. The American Journal of Medicine 2015 128, e15-e18DOI: (10.1016/j.amjmed.2015.05.009) Copyright © 2015 Elsevier Inc. Terms and Conditions