Antibiotic Exposure Promotes Fat Gain

Slides:



Advertisements
Similar presentations
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Advertisements

Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis Wing-Hang Tong, Tracey A. Rouault Cell.
PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors Joan Sanchez-Gurmaches, Chien-Min.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
Lipin-1 Regulates Autophagy Clearance and Intersects with Statin Drug Effects in Skeletal Muscle Peixiang Zhang, M. Anthony Verity, Karen Reue Cell Metabolism.
Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:
30 AUGUST 2012 | VOL 488 | NATURE R3 Jae Ryung Shin/Prof. Sang Youl Rhee.
Oxygen Sensors at the Crossroad of Metabolism Julián Aragonés, Peter Fraisl, Myriam Baes, Peter Carmeliet Cell Metabolism Volume 9, Issue 1, Pages
One Strike against Low-Carbohydrate Diets
The ART of Lowering Ceramides
Volume 14, Issue 2, Pages (August 2011)
Elaine Holmes, Jia V. Li, Julian R. Marchesi, Jeremy K. Nicholson 
Interleukins and Atherosclerosis: A Dysfunctional Family Grows
Herbert Tilg, Timon E. Adolph  Cell Metabolism 
Energy Sparing Orexigenic Inflammation of Obesity
Bariatric Surgery Restores Gut-Brain Signaling to Reduce Fat Intake
Volume 18, Issue 4, Pages (October 2015)
Specialized Metabolites from the Microbiome in Health and Disease
Does Hypothalamic Inflammation Cause Obesity?
More Than Satiety: Central Serotonin Signaling and Glucose Homeostasis
In and Out: Adipose Tissue Lipid Turnover in Obesity and Dyslipidemia
Gut Microbiota: The Link to Your Second Brain
Omega 3 Fatty Acids and GPR120
Serotonin and the Orchestration of Energy Balance
SCFAs Take a Toll En Route to Metabolic Syndrome
Volume 12, Issue 5, Pages (November 2010)
SUMOylation Places LRH-1 in PROXimity to Lipid Metabolism
Gut Microbes Make for Fattier Fish
Adipose Tissue Macrophages: Amicus adipem?
Pascal Ferré, Fabienne Foufelle  Cell Metabolism 
Assessment of Feeding Behavior in Laboratory Mice
Come on BAIBA Light My Fire
Dysfunctional Families: Clostridium scindens and Secondary Bile Acids Inhibit the Growth of Clostridium difficile  K. Leigh Greathouse, Curtis C. Harris,
SUMOylation Places LRH-1 in PROXimity to Lipid Metabolism
Is Predisposition to NAFLD and Obesity Communicable?
Specialized Metabolites from the Microbiome in Health and Disease
Chapter 65 - The Hormonal Regulation of Calcium Metabolism
Treating Obesity? It's in the Bag!
Heike Döppler, Peter Storz  Cell Metabolism 
One Strike against Low-Carbohydrate Diets
Irisin, Turning Up the Heat
Autophagy: A Sweet Process in Diabetes
Making Biological Sense of GWAS Data: Lessons from the FTO Locus
Chad M. Trent, Martin J. Blaser  Cell Metabolism 
It’s in the Milk: Feeding the Microbiome to Promote Infant Growth
IL-6 Muscles In on the Gut and Pancreas to Enhance Insulin Secretion
NRG4: An Endocrine Link between Brown Adipose Tissue and Liver
Branching Out for Detection of Type 2 Diabetes
Leucing Weight with a Futile Cycle
Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism  David Carling, Benoit Viollet  Cell Metabolism 
In and Out: Adipose Tissue Lipid Turnover in Obesity and Dyslipidemia
Lasker Lauds Leptin Cell Metabolism
Gut Microbes Make for Fattier Fish
Dietary Carbohydrates Impair Healthspan and Promote Mortality
Do Cancer Cells Care If Their Host Is Hungry?
Asthma Prevention: Right Bugs, Right Time?
Volume 14, Issue 2, Pages (August 2011)
Dietary Fructose Metabolism By Splanchnic Organs: Size Matters
Adipose Dendritic Cells Come Out of Hiding
Protein nutrition as therapy for a genetic disorder of bone?
Treating Diabetes by Blocking a Vascular Growth Factor
AgRP in energy balance: Will the real AgRP please stand up?
Of Mice and Men: Not ExAKTly the Same?
Rejuvenation: It’s in Our Blood
Estrogens and Obesity: Is It All in Our Heads?
Presentation transcript:

Antibiotic Exposure Promotes Fat Gain Alice P. Liou, Peter J. Turnbaugh  Cell Metabolism  Volume 16, Issue 4, Pages 408-410 (October 2012) DOI: 10.1016/j.cmet.2012.09.009 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 The Many Effects of Subtherapeutic Antibiotic Treatment on Young Mice Relative to control mice, STAT results in similar total body weight but increased adiposity, dietary energy harvest, bone mineral density (BMD), and short-chain fatty acid (SCFA) levels. These phenotypic differences were associated with changes to the gut microbial community, host lipid metabolism, and gut hormone signaling. Future studies promise to elucidate the mechanistic basis for these changes. Cell Metabolism 2012 16, 408-410DOI: (10.1016/j.cmet.2012.09.009) Copyright © 2012 Elsevier Inc. Terms and Conditions