Volume 71, Issue 5, Pages 766-773 (May 2017) Clinical Outcomes for Patients with Gleason Score 9–10 Prostate Adenocarcinoma Treated With Radiotherapy or Radical Prostatectomy: A Multi-institutional Comparative Analysis  Amar U. Kishan, Talha Shaikh, Pin-Chieh Wang, Robert E. Reiter, Jonathan Said, Govind Raghavan, Nicholas G. Nickols, William J. Aronson, Ahmad Sadeghi, Mitchell Kamrava, David Jeffrey Demanes, Michael L. Steinberg, Eric M. Horwitz, Patrick A. Kupelian, Christopher R. King  European Urology  Volume 71, Issue 5, Pages 766-773 (May 2017) DOI: 10.1016/j.eururo.2016.06.046 Copyright © 2016 European Association of Urology Terms and Conditions

Fig. 1 Kaplan-Meier curves distant metastasis (DM)-free survival. The curves have not been adjusted for age, Gleason score, clinical stage, initial prostate-specific antigen, year of treatment, or utilization of local or systemic salvage therapies (with salvage treated as a time-dependent variable). Following multivariate regression adjusted for these factors, patients treated with external beam radiotherapy+brachytherapy (brachy; EBRT+BT) had significantly higher 5-yr and 10-yr DM-free survival rates than patients treated with either radical prostatectomy (RP) or EBRT (p<0.01 for both). European Urology 2017 71, 766-773DOI: (10.1016/j.eururo.2016.06.046) Copyright © 2016 European Association of Urology Terms and Conditions

Fig. 2 (A) Kaplan-Meier curves for cancer-specific survival. (B) Kaplan-Meier curves for overall survival. The curves have not been adjusted for age, Gleason score, clinical stage, or prostate-specific antigen. Following multivariate regression adjusted for these factors, all patients had statistically similar 5-yr and 10-yr cancer-specific survival and overall survival rates. brachy=brachytherapy; EBRT=external beam radiotherapy; RP=radical prostatectomy. European Urology 2017 71, 766-773DOI: (10.1016/j.eururo.2016.06.046) Copyright © 2016 European Association of Urology Terms and Conditions