The Case of the Missed Chest Radiograph: Bilateral Mammary Gland Metastases Mimicking Multifocal Primary Breast Cancer as the Initial Manifestation of.

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Presentation transcript:

The Case of the Missed Chest Radiograph: Bilateral Mammary Gland Metastases Mimicking Multifocal Primary Breast Cancer as the Initial Manifestation of Non–Small- Cell Lung Cancer  Giannis Mountzios, MD, PhD, Anastasios Gyftopoulos, Eleni Vlotinou, Nikolaos Kentepozidis, MD, PhD  Journal of Thoracic Oncology  Volume 9, Issue 11, Pages 1729-1731 (November 2014) DOI: 10.1097/JTO.0000000000000265 Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Mammographic images of the left (A) and right (B) breast. Mediolateral oblique view. Journal of Thoracic Oncology 2014 9, 1729-1731DOI: (10.1097/JTO.0000000000000265) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 A and B, Hematoxylin-Eosin staining of the left breast tumor showing massive infiltration of the mammary gland by a poorly differenetiated carcinoma comprising medium and large-size cells with hyperdense nuclei (A, magnification × 10; B, magnification × 100). C, Strong positive staining of the tumor cells for thyroid transcription factor 1 (TTF1) (magnification × 40). Journal of Thoracic Oncology 2014 9, 1729-1731DOI: (10.1097/JTO.0000000000000265) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Computed tomography scan of the thorax showing the left lung mass extending from the left apex to the left hilar region with lobular margins (A, coronal axis), the enlarged paratracheal, subcarinal and left hilar lymph nodes (B, vertical axis), the left breast mass fixed on the left thoracic wall (C, vertical axis, white arrow), the encapsulation of the upper lobar branch of the left main pulmonary artery (D, vertical axis, long black arrow), and the same image in soft-tissue algorithm (E, vertical axis). Journal of Thoracic Oncology 2014 9, 1729-1731DOI: (10.1097/JTO.0000000000000265) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions