Complicated Clostridium difficile colitis in children with cystic fibrosis: Association with gastric acid suppression? G. Com, N. Cetin, C.E. O'Brien

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Presentation transcript:

Complicated Clostridium difficile colitis in children with cystic fibrosis: Association with gastric acid suppression? G. Com, N. Cetin, C.E. O'Brien Journal of Cystic Fibrosis Volume 13, Issue 1, Pages 37-42 (January 2014) DOI: 10.1016/j.jcf.2013.08.005 Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Case #3, prior to total colectomy. Diffuse colonic wall edema and dilation of colon associated with toxic megacolon. Journal of Cystic Fibrosis 2014 13, 37-42DOI: (10.1016/j.jcf.2013.08.005) Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 The post-operative pathology sample shows a thick pseudomembrane formed by neutrophils, epithelial debris, red blood cells, fibrin, and mucus adheres to the colonic mucosa (A) and exudate erupting from areas of mucosal erosion resembling lava erupting from a volcano (B). Journal of Cystic Fibrosis 2014 13, 37-42DOI: (10.1016/j.jcf.2013.08.005) Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions