Malignant Progenitors From Patients With Acute Myelogenous Leukemia Are Sensitive to a Diphtheria Toxin–Granulocyte-Macrophage Colony-Stimulating Factor Fusion Protein by Donna E. Hogge, Cheryl L. Willman, Robert J. Kreitman, Marc Berger, Philip D. Hall, Kenneth J. Kopecky, Chris McLain, Edward P. Tagge, Connie J. Eaves, and Arthur E. Frankel Blood Volume 92(2):589-595 July 15, 1998 ©1998 by American Society of Hematology

Scatchard plot of the blasts of patient no. 1 with 3 Scatchard plot of the blasts of patient no. 1 with 3.36 × 106 cells per aliquot and 125I-GM-CSF specific activity of 84 μCi/μg. Scatchard plot of the blasts of patient no. 1 with 3.36 × 106 cells per aliquot and 125I-GM-CSF specific activity of 84 μCi/μg. The lower 6 concentrations and the higher 4 concentrations were analyzed separately and the r2values on both are .98. Donna E. Hogge et al. Blood 1998;92:589-595 ©1998 by American Society of Hematology

Colony growth inhibition after exposure of cells to DT388-GMCSF in liquid culture for 48 hours followed by their plating in semisolid medium at 17 days (patient no. 34). Colony growth inhibition after exposure of cells to DT388-GMCSF in liquid culture for 48 hours followed by their plating in semisolid medium at 17 days (patient no. 34). Donna E. Hogge et al. Blood 1998;92:589-595 ©1998 by American Society of Hematology