Atopic Dermatitis. Introduction to a Clinical Course On New Developments In Atopic Dermatitis.

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Presentation transcript:

Introduction to a Clinical Course On New Developments In Atopic Dermatitis

Atopic Dermatitis

Program Overview

Atopic dermatitis: burden and impact

Atopic Dermatitis: Clinical Presentation

Psychological Burden of Skin Diseases: Atopic Dermatitis

Atopic Dermatitis: Current Management Options

Current Management: Moderate to Severe Atopic Dermatitis

Case of a Woman With Lifelong History of Atopic Dermatitis

Concluding Remarks

Characterizing atopic dermatitis: going beneath the skin

Introduction

Nonlesional Skin in Atopic Dermatitis Shows Abnormal Cytokine Profile

Paradigm Shift in the Pathogenesis of Atopic Dermatitis

Same Pathways in Adults and Children?

Pediatric vs Adult Skin in Atopic Dermatitis

Test of Immune Hypothesis With Dupilumab

Patients on Higher Doses Achieved EASI-50

Reduction in Epidermal Hyperplasia After 4 Weeks of Dupilumab Treatment

Suppression of Th2 and Other Axes

Other Targets in Clinical Trials for Atopic Dermatitis

Concluding Remarks

Setting standards in atopic dermatitis management

Treatment Guidelines and Recommendations for Atopic Dermatitis

Measuring Disease Activity: ETFAD

Treatment Options by Grade of Atopic Dermatitis

Systemic Immunosuppressants for Severe Atopic Dermatitis

Treatment Options for Moderate Atopic Dermatitis

Concluding Remarks

Biological therapy for atopic dermatitis: new developments

Introduction

Role of Th2 in Atopic Dermatitis

SOLO 1 and 2 Phase 3 Results: Dupilumab

SOLO 1 and 2 Phase 3 Results: Depression Scores

Interaction With Many Pathways: Example of Cyclosporine

SOLO 1 and 2: Safety and Tolerability

Dupilumab in Asthma and Nasal Polyps

Other Targets in Clinical Trials for Atopic Dermatitis

Atopic Dermatitis and Comorbidities

Patient Case of Severe Atopic Dermatitis

Looking into the future: emerging therapeutic pathways in atopic dermatitis

Novel Developments in the Understanding of Atopic Dermatitis

Future Potential of New Biologic Therapies

Importance of Restoring Barrier Function

Concluding Remarks

Abbreviations

Abbreviations