2-[18F]fluoro-2-deoxy-d-galactose positron emission tomography guided functional treatment planning of stereotactic body radiotherapy of liver tumours

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2-[18F]fluoro-2-deoxy-d-galactose positron emission tomography guided functional treatment planning of stereotactic body radiotherapy of liver tumours Mette Marie Fode, Jørgen Baltzer Petersen, Michael Sørensen, Marianne Ingerslev Holt, Susanne Keiding, Morten Høyer Physics and Imaging in Radiation Oncology Volume 1, Pages 28-33 (January 2017) DOI: 10.1016/j.phro.2017.02.002 Copyright © 2017 The Authors Terms and Conditions

Fig. 1 The heterogeneous distribution standard uptake value (SUV) of 2-[18F]flouro-2-deoxy-d-galactose positron emission tomography (FDGal PET) before stereotactic body radiotherapy (SBRT) in patient #4. The radioactivity in the liver and the renal excretion is visualised. Physics and Imaging in Radiation Oncology 2017 1, 28-33DOI: (10.1016/j.phro.2017.02.002) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 Anatomical treatment plan (ATP) versus functional treatment plan (FTP) in patient #4. Sub-volumes of iso-functioning liver were contoured as 10% (V′10%) (pink), 20% (V′20%) (brown) and 30% (V′30%) (blue) of the best functioning liver tissue at FDGal PET and the contours were transferred to the planning CT. A: Dose volume histogram (DVH): V′10%, V′20%, V′30% of the best functioning liver tissue, liver-CTV (green); B: V′10%, V′20%, V′30% of the best functioning liver tissue at FDGal PET, CTV (red); C: Dose color wash at 67% iso-dose (37.5Gy), ATP; D: Dose color wash at 67% iso-dose (37.5Gy), FTP; E: The volume of the liver (CTV excluded) that received less than 15Gy (VD<15Gy), ATP; F: VD<15Gy, FTP. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.) Physics and Imaging in Radiation Oncology 2017 1, 28-33DOI: (10.1016/j.phro.2017.02.002) Copyright © 2017 The Authors Terms and Conditions

Fig. 3 Percentage difference in mean dose (Dmean) in V′10%, V′20% and V′30% best functioning liver tissue in seven patients. Physics and Imaging in Radiation Oncology 2017 1, 28-33DOI: (10.1016/j.phro.2017.02.002) Copyright © 2017 The Authors Terms and Conditions