Alzheimer’s Disease Genetics: From the Bench to the Clinic

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Alzheimer’s Disease Genetics: From the Bench to the Clinic Celeste M. Karch, Carlos Cruchaga, Alison M. Goate Neuron Volume 83, Issue 1, Pages 11-26 (July 2014) DOI: 10.1016/j.neuron.2014.05.041 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Cell-Type Expression of Alzheimer’s Disease Risk Genes May Influence AD Pathogenesis The major cell types present in the brain are depicted. Genes are listed in the cell type in which they are most highly expressed (B. Barres, personal communication). GWAS loci that contain multiple genes were excluded from this figure, as it remains unclear which gene is responsible for the signal (CR1, BIN1, PICALM, HLA, SLC24A4, DSG2, ZCWPW1, CELF1, FERMT2, CASS4). Neuron 2014 83, 11-26DOI: (10.1016/j.neuron.2014.05.041) Copyright © 2014 Elsevier Inc. Terms and Conditions