Heart failure and movement-induced hemodynamics: Partitioning the impact of central and peripheral dysfunction Melissa A.H. Witman, Stephen J. Ives,

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Presentation transcript:

Heart failure and movement-induced hemodynamics: Partitioning the impact of central and peripheral dysfunction Melissa A.H. Witman, Stephen J. Ives, Joel D. Trinity, H. Jonathan Groot, Josef Stehlik, Russell S. Richardson International Journal of Cardiology Volume 178, Pages 232-238 (January 2015) DOI: 10.1016/j.ijcard.2014.10.044 Copyright © 2014 Terms and Conditions

Fig. 1 Peripheral hemodynamic responses to continuous PLM in controls and patients with HFrEF. Data are presented as mean±SE for femoral blood flow (A), femoral blood flow area under the curve (AUC) (B), leg vascular conductance (C), and leg vascular conductance AUC (D). The transition from baseline to movement occurs at 0 on the axis. International Journal of Cardiology 2015 178, 232-238DOI: (10.1016/j.ijcard.2014.10.044) Copyright © 2014 Terms and Conditions

Fig. 2 Central hemodynamic responses to continuous PLM in controls and patients with HFrEF. Data are presented as mean±SE for heart rate (A), stroke volume (B), cardiac output (C), and mean arterial pressure (D) across time. Note: These figures are presented to illustrate the general trends. As the analyses were performed on data from individuals who exhibited varying response kinetics, averaging removes some of the information in the original individual recordings. Therefore, maximum change is represented in the upper corner of each figure. International Journal of Cardiology 2015 178, 232-238DOI: (10.1016/j.ijcard.2014.10.044) Copyright © 2014 Terms and Conditions

Fig. 3 Peripheral hemodynamic responses to single PLM in controls and patients with HFrEF. Data are presented as mean±SE of femoral blood flow (A), femoral blood flow area under the curve (AUC) (B), leg vascular conductance (C), and leg vascular conductance AUC (D). The transition from baseline to movement occurs at 0 on the axis. International Journal of Cardiology 2015 178, 232-238DOI: (10.1016/j.ijcard.2014.10.044) Copyright © 2014 Terms and Conditions

Fig. 4 Central hemodynamic responses to single PLM in controls and patients with HFrEF. Data are presented as mean±SE of heart rate (A), stroke volume (B), cardiac output (C), and mean arterial pressure (D) across time. Note: These time plots are presented to illustrate the general trends. As the analyses were performed on data from individuals who exhibited varying response kinetics, averaging removes some of the information in the original individual recordings. Therefore, maximum change is represented in the upper corner of each figure. International Journal of Cardiology 2015 178, 232-238DOI: (10.1016/j.ijcard.2014.10.044) Copyright © 2014 Terms and Conditions