Mammalian PGRPs Also Mind the Fort

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Mammalian PGRPs Also Mind the Fort Stephen Rubino, Jooeun Lee, Stephen E. Girardin  Cell Host & Microbe  Volume 8, Issue 2, Pages 130-132 (August 2010) DOI: 10.1016/j.chom.2010.07.010 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 PGRPs Tip the Balance toward an Anti-Inflammatory Microbiota Peptidoglycan recognition proteins (PGRPs) play an anti-inflammatory role in the gastro-intestinal (GI) mucosa by promoting the production of anti-inflammatory microflora, such as Lactobacillus species, thus limiting IFN-γ production by natural killer (NK) cells during acute intestinal injury triggered by dextran sulfate sodium (DSS). Cell Host & Microbe 2010 8, 130-132DOI: (10.1016/j.chom.2010.07.010) Copyright © 2010 Elsevier Inc. Terms and Conditions