The First High-Resolution DNA “Methylome”

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The First High-Resolution DNA “Methylome” Hanspeter Schöb, Ueli Grossniklaus Cell Volume 126, Issue 6, Pages 1025-1028 (September 2006) DOI: 10.1016/j.cell.2006.09.002 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 The Establishment and Maintenance of DNA Methylation in Arabidopsis Establishment and maintenance of DNA methylation at different sequence contexts in Arabidopsis is controlled by different pathways and requires targeting by the RNAi machinery as well as by histone modifications. Modes of maintenance of DNA methylation differ in that the inheritance of CG methylation can be coupled to DNA replication, independent of siRNAs and histone modifications. (Figure adapted from Chan et al., 2006.) Abbreviations: DRM1/2, DOMAINS REARRANGED METHYLTRANSFERASES 1/2; DRD1, DEFECTIVE IN RNA-MEDIATED DNA METHYLATION 1; CMT3, CHROMOMETHYLASE 3; MET1, METHYLTRANSFERASE 1; DDM1, DECREASE IN DNA METHYLATION 1. Cell 2006 126, 1025-1028DOI: (10.1016/j.cell.2006.09.002) Copyright © 2006 Elsevier Inc. Terms and Conditions