Intraoperative physiologic variables and outcome in cardiac surgery: part II. Neurologic outcome Gijs K van Wermeskerken, MD, Jan-Willem H Lardenoye,

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Intraoperative physiologic variables and outcome in cardiac surgery: part II. Neurologic outcome Gijs K van Wermeskerken, MD, Jan-Willem H Lardenoye, MD, Steven E Hill, MD, Hilary P Grocott, MD, Barbara Phillips-Bute, PhD, Peter K Smith, MD, Joseph G Reves, MD, Mark F Newman, MD The Annals of Thoracic Surgery Volume 69, Issue 4, Pages 1077-1083 (April 2000) DOI: 10.1016/S0003-4975(99)01443-5

Fig 1 Probability of adverse neurologic event in relation to mean arterial pressure less than 50 mm Hg (MAP < 50) controlling for stroke risk index and cardiopulmonary bypass time. The upper and lower lines represent the 95% confidence intervals. A more negative MAP < 50 (greater time and extent of mean arterial pressure depression less than 50 mm Hg) is associated with a decreased risk of adverse neurologic outcome (p = 0.0304; c-index for model = 0.714). The Annals of Thoracic Surgery 2000 69, 1077-1083DOI: (10.1016/S0003-4975(99)01443-5)

Fig 2 Probability of an adverse neurologic event in normal to high (HI) mean arterial pressure (MAP) and low (LO) MAP groups stratified into quartiles by stroke risk index score. The association between lower pressure during cardiopulmonary bypass and less neurologic injury persisted in each of the four risk groups (n = 708 to 731 patients per quartile). The Annals of Thoracic Surgery 2000 69, 1077-1083DOI: (10.1016/S0003-4975(99)01443-5)