Genome-Wide Association Analysis Implicates Elastic Microfibrils in the Development of Nonsyndromic Striae Distensae  Joyce Y. Tung, Amy K. Kiefer, Meghan.

Slides:



Advertisements
Similar presentations
Pigmentation-Independent Susceptibility Loci for Actinic Keratosis Highlighted by Compound Heterozygosity Analysis  Kaiyin Zhong, Joris A.C. Verkouteren,
Advertisements

Francesca Capon  Journal of Investigative Dermatology 
Ruth Kimmelstiel Freinkel (1926–2014)
A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots  Leonie C. Jacobs, Merel.
Correction to: “Journal of Investigative Dermatology” advance online publication, 9 April 2015; doi: /jid   Emilie S. Chan, Leal C. Herlitz,
A New View of Vitiligo: Looking at Normal-Appearing Skin
Linkage and Association Analysis of Spectrophotometrically Quantified Hair Color in Australian Adolescents: the Effect of OCA2 and HERC2  Sri N. Shekar,
Clinical Snippets Journal of Investigative Dermatology
Anne L. S. Chang, Gil Atzmon, Aviv Bergman, Samantha Brugmann, Scott X
Irwin Freedberg: Physician-Scientist and Mentor
Kavitha K. Reddy  Journal of Investigative Dermatology 
Databases for Clinical Research
Complex Role of TNF Variants in Psoriatic Arthritis and Treatment Response to Anti- TNF Therapy: Evidence and Concepts  Ulrike Hüffmeier, Rotraut Mössner 
Assessment of the Genetic Basis of Rosacea by Genome-Wide Association Study  Anne Lynn S. Chang, Inbar Raber, Jin Xu, Rui Li, Robert Spitale, Julia Chen,
Genetic Investigations of Kidney Disease: Core Curriculum 2013
Systematic Linkage Disequilibrium Analysis of SLC12A8 at PSORS5 Confirms a Role in Susceptibility to Psoriasis Vulgaris  Ulrike Hüffmeier, Jesús Lascorz,
Toward Improved Understanding of a Potential Association between Isotretinoin and Inflammatory Bowel Disease  Alisa N. Femia, Ruth Ann Vleugels  Journal.
A Genome-Wide Association Study in Caucasian Women Points Out a Putative Role of the STXBP5L Gene in Facial Photoaging  Sigrid Le Clerc, Lieng Taing,
Circulating Tumor Cells and Melanoma Progression
Genome-Wide Analysis Identifies a Quantitative Trait Locus in the MHC Class II Region Associated with Generalized Vitiligo Age of Onset  Ying Jin, Stanca.
Meeting Report from Frontiers in Ichthyosis Research
Post-IID 2008 International Meeting on Autoimmune Bullous Diseases
John P. Sundberg, Derry C. Roopenian, Edison T. Liu, Paul N. Schofield 
The Thinning Top: Why Old People Have Less Hair
Alice Pentland  Journal of Investigative Dermatology 
Clinical Snippets Journal of Investigative Dermatology
Minutes of the Board of Directors Meeting
Maryam M. Asgari, Wei Wang, Nilah M
Volume 380, Issue 9844, Pages (September 2012)
Template-Directed Dye-Terminator Incorporation with Fluorescence Polarization Detection for Analysis of Single Nucleotide Polymorphisms Implicated in.
Star Trek Publishing Journal of Investigative Dermatology
JID VisualDx Quiz: May 2014 Journal of Investigative Dermatology
KIT in Melanoma: Many Shades of Gray
Clinical Snippets Journal of Investigative Dermatology
Lopa M. Das, Kurt Q. Lu  Journal of Investigative Dermatology 
High-Density Lipoprotein Cholesterol Function Improves after Successful Treatment of Psoriasis: A Step Forward in the Right Direction  Nehal N. Mehta,
Journal of Investigative Dermatology
Journal of Investigative Dermatology 
CXCR4 in Epidermal Keratinocytes: Crosstalk within the Skin
Society for Investigative Dermatology 2010 Meeting Minutes
Journal of Investigative Dermatology
Democratizing the Clinical Trials Agenda in Dermatology
Maria T. García-Romero, Roberto Arenas 
BJD Editor's Choice Journal of Investigative Dermatology
Tomoo Ohashi  Journal of Investigative Dermatology 
Cells of Origin in Skin Cancer
Ying Jin, Stanca A. Birlea, Pamela R. Fain, Richard A. Spritz 
Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes  Shenying Fang, Yuling Wang, Yun S. Chun,
Research Snippets Journal of Investigative Dermatology
Clinical Snippets Journal of Investigative Dermatology
Journal of Investigative Dermatology
How Much Sun Protection Is Needed
BJD Editor’s Choice Journal of Investigative Dermatology
Genetic Influences on Human Body Odor: From Genes to the Axillae
Interpretation of Skindex-29 Scores
Metabolic Vulnerability in Melanoma: A ME2 (Me Too) Story
Research Snippets from the British Journal of Dermatology
Melanocyte Regeneration in Vitiligo Requires WNT beneath their Wings
TLR3: A Receptor that Recognizes Cell Injury Is Essential for Permeability Barrier Homeostasis Following UV Irradiation  Kenneth R. Feingold  Journal.
25 Years of Epidermal Stem Cell Research
Journal of Investigative Dermatology
Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximity to IDDM8   Stanca.
Research Snippets Journal of Investigative Dermatology
Journal of Investigative Dermatology
Consequences of Psychological Distress in Adolescents with Acne
Psoriasis Genetics: The Way Forward
Journal of Investigative Dermatology
Journal of Investigative Dermatology
Journal of Investigative Dermatology
Innate Immunity Stimulates Permeability Barrier Homeostasis
Presentation transcript:

Genome-Wide Association Analysis Implicates Elastic Microfibrils in the Development of Nonsyndromic Striae Distensae  Joyce Y. Tung, Amy K. Kiefer, Meghan Mullins, Uta Francke, Nicholas Eriksson  Journal of Investigative Dermatology  Volume 133, Issue 11, Pages 2628-2631 (November 2013) DOI: 10.1038/jid.2013.196 Copyright © 2013 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Manhattan plot depicting single-nucleotide polymorphism (SNP) associations with stretch marks. (a) Genome-wide view of associations. SNPs shown in red are genome-wide significant (P<5e-8). Regions are named with the postulated candidate gene. (b) Detailed view of local region around rs7787362. Colors depict the squared correlation (r2) of each SNP with rs7787362, shown in purple. Gray indicates SNPs for which r2 information was missing. Journal of Investigative Dermatology 2013 133, 2628-2631DOI: (10.1038/jid.2013.196) Copyright © 2013 The Society for Investigative Dermatology, Inc Terms and Conditions