Volume 147, Issue 3, Pages e1 (September 2014)

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Volume 147, Issue 3, Pages 599-601.e1 (September 2014) Detection of a Sexually Transmitted Hepatitis C Virus Protease Inhibitor-Resistance Variant in a Human Immunodeficiency Virus–Infected Homosexual Man Sandra Franco, Cristina Tural, Maria Nevot, José Moltó, Jürgen Kurt Rockstroh, Bonaventura Clotet, Miguel Angel Martinez Gastroenterology Volume 147, Issue 3, Pages 599-601.e1 (September 2014) DOI: 10.1053/j.gastro.2014.05.010 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 Phylogenetic relationship of HCV NS3 protease sequences obtained from patients A and B and from another 26 patients attending our clinic.6 Bootstrap analysis (100 repetitions) was performed to determine the reliability of the sample grouping (numbers at branch nodes). An asterisk indicates an NS3 protease clone carrying the resistance genotype. Phylogenetic analysis was performed using the MEGA5 software package with a Kimura 2-parameter model of evolution.7 The HCV NS3 sequences obtained and characterized in this study were submitted to the GenBank database under the following accession numbers: KF998821-KF998916 and KJ710776-KJ710859. Gastroenterology 2014 147, 599-601.e1DOI: (10.1053/j.gastro.2014.05.010) Copyright © 2014 AGA Institute Terms and Conditions