Prostate Imaging-Reporting and Data System Steering Committee: PI-RADS v2 Status Update and Future Directions  Anwar R. Padhani, Jeffrey Weinreb, Andrew.

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Prostate Imaging-Reporting and Data System Steering Committee: PI-RADS v2 Status Update and Future Directions  Anwar R. Padhani, Jeffrey Weinreb, Andrew B. Rosenkrantz, Geert Villeirs, Baris Turkbey, Jelle Barentsz  European Urology  DOI: 10.1016/j.eururo.2018.05.035 Copyright © 2018 The Author(s) Terms and Conditions

Fig. 1 Prostate cancer diagnostic pathway: benefits of incorporating mpMRI, PI-RADS scoring and MRDB sampling. (1) Greater precision in determining tumor grade and volume (improved risk stratification and higher precision in making therapy choices). (2) Potential higher rates of detection of clinically significant disease needing active treatments. (3) Potential reductions in diagnosis of indolent disease, thereby reducing overdiagnosis and overtreatment. (4) Fewer targeted biopsies per patient required to make effective diagnoses and minimization of biopsy-related morbidity. (5) Reduction in the number of patients undergoing biopsy. mpMRI=multiparametric magnetic resonance imaging; PI-RADS=Prostate Imaging-Reporting and Data System; MRDB=magnetic resonance–directed biopsy; MDT=multidisciplinary team; PSAD=prostate-specific antigen density. European Urology DOI: (10.1016/j.eururo.2018.05.035) Copyright © 2018 The Author(s) Terms and Conditions