Ovarian response to the human chorionic gonadotrophin stimulation test in normal ovulatory women: the impact of regressing corpus luteum Ilkka Y. Järvelä,

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Presentation transcript:

Ovarian response to the human chorionic gonadotrophin stimulation test in normal ovulatory women: the impact of regressing corpus luteum Ilkka Y. Järvelä, M.D., Maarit Niinimäki, M.D., Hannu Martikainen, M.D., Aimo Ruokonen, M.D., Juha S. Tapanainen, M.D. Fertility and Sterility Volume 87, Issue 5, Pages 1122-1130 (May 2007) DOI: 10.1016/j.fertnstert.2006.08.114 Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Three-dimensional power Doppler ultrasonographic images of an ovary with a rescued CL (right) and the contralateral ovary (left) 96 hours after hCG injection. The CL is surrounded by an extensive vascular network (white arrow). The volume of the left ovary was 6.0 mL, and the volume of the vasculature was 0.3 mL. On the right side, the measurements were 17.0 mL and 2.8 mL, respectively. Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007.Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007. Fertility and Sterility 2007 87, 1122-1130DOI: (10.1016/j.fertnstert.2006.08.114) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Responses of serum P (A), 17-OHP (B), A (C), T (D), E2 (E), and FSH (F) to a single dose of hCG (5,000 IU) in women with and without a CL. *Statistical significance between the groups at each time point, P<.05. Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007.Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007. Fertility and Sterility 2007 87, 1122-1130DOI: (10.1016/j.fertnstert.2006.08.114) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 3 Responses of ovarian total (A), vascularized (B), and nonvascularized (C) volume to a single dose of hCG (5,000 IU) in women with and without a CL. In the CL+ group, the ovary containing the CL and the contralateral ovary are presented separately. In the control group (no CL), the values represent the mean of both ovaries. *Statistical significance between the CL+ ovary and the control group at each time point, P<.05; ‡statistical significance between the CL+ ovary and the contralateral ovary at each time point, P<.05. Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007.Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007. Fertility and Sterility 2007 87, 1122-1130DOI: (10.1016/j.fertnstert.2006.08.114) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 4 Correlations of AUCs between P, 17-OHP, and ovarian volume and vascularization. In the CL+ group, volume and vascularization concern only the CL-containing ovary. In the CL− group (no CL, control group), volume and vascularization are means of both ovaries. Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007.Järvelä. hCG test and regressing corpus luteum. Fertil Steril 2007. Fertility and Sterility 2007 87, 1122-1130DOI: (10.1016/j.fertnstert.2006.08.114) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions