Program Goals

Disclaimer

Overview

Assessing Disease Activity

Assessing Disease Activity (cont)

Surveillance Monitoring

Modified Rio Score

How Much Time Should Be Allowed to Determine Whether a DMT Is Effective?

Does Switching Work?

Stopping Natalizumab Treatment

Tolerability Issues

JCV Serology

Is a Washout Period Needed?

Is a Washout Period Needed? (cont)

Rebound

Selecting the Next Treatment Option: General Principles

Guidelines About Switching Are Lacking

Summary and Key Points

Abbreviations

References

References (cont)

References (cont)

References (cont)

References (cont)