David L. McCollum, J. Martin Rodriguez 

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Detection, Treatment, and Prevention of Clostridium difficile Infection  David L. McCollum, J. Martin Rodriguez  Clinical Gastroenterology and Hepatology  Volume 10, Issue 6, Pages 581-592 (June 2012) DOI: 10.1016/j.cgh.2012.03.008 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 The pathogenesis of CDI involves disruption in the normal intestinal microbiota, followed by colonization with toxin-producing strains of C difficile (A) and release of toxins (B) leading to cell death, inflammation, and symptoms (C). Clinical Gastroenterology and Hepatology 2012 10, 581-592DOI: (10.1016/j.cgh.2012.03.008) Copyright © 2012 AGA Institute Terms and Conditions