A presentation to: Meeting name Date

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A presentation to: Meeting name Date Conjunctival autograft for pterygium Elizabeth Clearfield, Valliammai Muthappan, Xue Wang, Irene C Kuo Issue 2, 2016 A presentation to: Meeting name Date

Table of Contents 01 Background 02 Types of studies 03 Key results 04 Tables (Risk of Bias/Forest Plots) 05 Conclusions 06 Acknowledgements

01: Background A pterygium is a growth from the conjunctiva, which can impair eye movement and vision, as well as cause irritiation Surgery is the only treatment Objective: To assess the safety and effectiveness of conjunctival autograft (with or without adjunctive therapy) compared with amniotic membrane graft (with or without adjunctive therapy) for pterygium

02: Types of studies Participants 20 randomized controlled trials, 1947 eyes of 1866 participants Interventions Conjunctival graft VERSUS Amniotic membrane transplant

03: Key results “The risk ratio for recurrence of pterygium using conjunctival autograft versus amniotic membrane transplant was 0.87 (95% CI 0.43 to 1.77) and 0.53 (95% CI 0.27 to 1.27) at 3 months and 6 months, respectively.”

04: Tables

04: Tables Recurrence of pterygium at 3 months

Recurrence of pterygium at 6 months

Adverse Events

05: Conclusions “In association with pterygium excision, conjunctival autograft is associated with a lower risk of recurrence at six months' after surgery than amniotic membrane transplant.”

06: Acknowledgements Cochrane Eyes and Vision US Satellite, funded by the National Eye Institute, National Institutes of Health Cochrane Eyes and Vision Editorial Base, funded by the UK National Health Service Research and Development Programme Elizabeth Clearfield, Valliammai Muthappan, Xue Wang, Irene C Kuo Review citation Clearfield E, Muthappan V, Wang X, Kuo IC. Conjunctival autograft for pterygium. Cochrane Database of Systematic Reviews 2016, Issue 2. Art. No.: CD011349. DOI: 10.1002/14651858.CD011349.pub2.