Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array W.-L. Huang, Z.-J. Hsu, T.C.

Slides:

Advertisements

Similar presentations

Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages

Advertisements

C.-S. Lee, J.-H. Lee Clinical Microbiology and Infection

Reduced turn-around time for Mycobacterium tuberculosis drug susceptibility testing with a proportional agar microplate assay V.A.T. Nguyen, H.Q. Nguyen,

Molecular evolution of Mycobacterium tuberculosis

Rapid diagnosis of pyrazinamide-resistant multidrug-resistant tuberculosis using a molecular-based diagnostic algorithm S.O. Simons, T. van der Laan,

Pyrazinamide resistance in multidrug-resistant Mycobacterium tuberculosis isolates in Japan H. Ando, S. Mitarai, Y. Kondo, T. Suetake, J.-I. Sekiguchi,

R. Dumke, H. von Baum, P.C. Lück, E. Jacobs

Helicobacter pylori resistance to antibiotics in 2014 in France detected by phenotypic and genotypic methods A. Ducournau, L. Bénéjat, E. Sifré, E. Bessède,

L. Boyanova Clinical Microbiology and Infection

High prevalence of azithromycin resistance to Treponema pallidum in geographically different areas in China X.-S. Chen, Y.-P. Yin, W.-H. Wei, H.-C. Wang,

Gut bacterial microbiota and obesity

Salvage therapy for multidrug-resistant tuberculosis

Control of multidrug-resistant Gram-negative bacteria in low- and middle-income countries—high impact interventions without much resources N. Singh,

Use of a high-density DNA probe array for detecting mutations involved in rifampicin resistance in Mycobacterium tuberculosis W. Sougakoff, M. Rodrigue,

C.-S. Lee, J.-H. Lee Clinical Microbiology and Infection

A novel strategy based on genomics and specific PCR reveals how a multidrug-resistant Mycobacterium tuberculosis strain became prevalent in Equatorial.

Virological tools to diagnose and monitor hepatitis C virus infection

G. Zhao, H. Zhai, Q. Yuan, S. Sun, T. Liu, L. Xie

Genotypic analysis of genes associated with transmission and drug resistance in the Beijing lineage of Mycobacterium tuberculosis J-R. Chang, C-H. Lin,

Whole genome analysis of Mycobacterium tuberculosis isolates from recurrent episodes of tuberculosis, Finland, 1995–2013 V. Korhonen, P.W. Smit, M. Haanperä,

GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in.

P. Nordmann, L. Poirel Clinical Microbiology and Infection

E. Cambau, M. Drancourt Clinical Microbiology and Infection

Genotypic characterization and historical perspective of Mycobacterium tuberculosis among older and younger Finns, 2008–2011 P.W. Smit, M. Haanperä,

Surveillance of Legionnaires’ disease in Austria

H. Adibhesami, M. Douraghi, M. Rahbar, A. Abdollahi

Vector control: a cornerstone in the malaria elimination campaign

Rapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolates using miniaturised oligonucleotide arrays S. Monecke, R. Ehricht Clinical.

Distribution of rpoB mutations among multidrug-resistant Mycobacterium tuberculosis (MDRTB) strains from Thailand and development of a rapid method for.

Characterization of Mycobacterium tuberculosis isolated from cancer patients with suspected tuberculosis infection in Egypt: identification, prevalence,

A new multiplex PCR for easy screening of methicillin-resistant Staphylococcus aureus SCCmec types I–V K. Boye, M.D. Bartels, I.S. Andersen, J.A. Møller,

Does it make sense to detect Streptococcus pyogenes during tonsillitis in Europe to prevent acute rheumatic fever? S. Edouard, A. Michel-Lepage, D. Raoult

Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience.

S. Borrell, S. Gagneux Clinical Microbiology and Infection

Salvage therapy for multidrug-resistant tuberculosis

L. Zhang, Q. Meng, S. Chen, M. Zhang, B. Chen, B. Wu, G. Yan, X

Clinical and microbiological characteristics of Nocardiosis including those caused by emerging Nocardia species in Taiwan, 1998–2008 C.-K. Tan, C.-C.

In vitro selection of antibiotic resistance in Pseudomonas aeruginosa

Metagenomics and probiotics

T.M. File Clinical Microbiology and Infection

Tuberculosis drug-resistance in Lisbon, Portugal: a 6-year overview

Update on antifungal resistance in Aspergillus and Candida

Harmonised monitoring of antimicrobial resistance in Salmonella and Campylobacter isolates from food animals in the European Union S. Bronzwaer Clinical.

Antibacterial drug discovery in the 21st century

Abstracts cont. Clinical Microbiology and Infection

Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A and B testing on stool samples J. Stahlmann,

Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial

Molecular epidemiology and virulence factors of pyogenic liver abscess causing Klebsiella pneumoniae in China Y. Luo, Y. Wang, L. Ye, J. Yang Clinical.

A novel fluorescence in situ hybridization test for rapid pathogen identification in positive blood cultures A. Makristathis, S. Riss, A.M. Hirschl

A.P. Underwood, J. Green Clinical Microbiology and Infection

Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan Y.-C. Hsieh, L.-Y. Chang, Y.-C. Huang, H.-C. Lin,

Increased in vitro fitness of multi- and extensively drug-resistant F15/LAM4/KZN strains of Mycobacterium tuberculosis C.C. Naidoo, M. Pillay Clinical.

H. Leblebicioglu, C. Eroglu Clinical Microbiology and Infection

Sequential time to positivity of blood cultures can be a predictor of prognosis of patients with persistent Staphylococcus aureus bacteraemia M.-S. Hsu,

Rapid identification of fungal pathogens in positive blood cultures using oligonucleotide array hybridization H-C. Hsiue, Y-T. Huang, Y-L. Kuo, C-H.

Presence of sandflies infected with Leishmania infantum and Massilia virus in the Marseille urban area† B. Faucher, R. Piarroux, C. Mary Clinical Microbiology.

Statin use and clinical outcomes among pneumonia patients

Clinical Microbiology and Infection

Potential association of specific Candida parapsilosis genotypes, bloodstream infections and colonization of health workers' hands D. Delfino, F. Scordino,

Modelling during an emergency: the 2009 H1N1 influenza pandemic

Detection of rpoB, katG and inhA gene mutations in Mycobacterium tuberculosis clinical isolates from Chongqing as determined by microarray C. Yao, T.

Susceptibility of multi-drug-resistant Pseudomonas aeruginosa in intensive care units: results from the European MYSTIC study group† H. Goossens Clinical.

J.L. Balcázar Clinical Microbiology and Infection

G.C. Schito Clinical Microbiology and Infection

Acquisition of second-line drug resistance and extensive drug resistance during recent transmission of Mycobacterium tuberculosis in rural China Y. Hu,

Impact of antibiotic restrictions: the patient's perspective

S.-H. Kung, S.-F. Wang, C.-W. Huang, C.-C. Hsu, H.-F. Liu, J.-Y. Yang

CMI readers' survey Clinical Microbiology and Infection

The future of diagnostic bacteriology

Long-term outcomes after nucleos(t)ide analogue discontinuation in HBeAg-positive chronic hepatitis B patients D. He, S. Guo, P. Zhu, S. Tao, M. Li,

Presentation transcript:

Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array W.-L. Huang, Z.-J. Hsu, T.C. Chang, R. Jou Clinical Microbiology and Infection Volume 20, Issue 9, Pages O542-O549 (September 2014) DOI: 10.1111/1469-0691.12517 Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Layout of probes on the array (a) position marker, (b) positive control, (c) internal amplification control and (d) wild-type probe. Clinical Microbiology and Infection 2014 20, O542-O549DOI: (10.1111/1469-0691.12517) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 The array and the GenoType MTBDRplus test yielded different results in some cases. Three multidrug-resistant Mycobacterium tuberculosis isolates (a–c) and one isoniazid (INH) mono-resistant isolate (d) were analysed with the array and the GenoType MTBDRplus test, and discrepant results were obtained. RIF, rifampin. Clinical Microbiology and Infection 2014 20, O542-O549DOI: (10.1111/1469-0691.12517) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions