Biomarkers in kidney fibrosis: are they useful?

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Biomarkers in kidney fibrosis: are they useful? Muh Geot Wong, Carol A. Pollock Kidney International Supplements Volume 4, Issue 1, Pages 79-83 (November 2014) DOI: 10.1038/kisup.2014.15 Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 1 The comparison of area under the curve (AUC) between urinary albumin creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), and circulating transforming growth factor-β1 (total and active TGFβ1) and bone morphogenetic protein-7 (BMP-7). Adding the biomarkers clearly provided an incremental c-statistic value to that of the known conventional markers. Akaike’s information criterion (AIC) showed the lowest value when all markers combined. (Adapted with permission from Wong et al.23) Kidney International Supplements 2014 4, 79-83DOI: (10.1038/kisup.2014.15) Copyright © 2014 International Society of Nephrology Terms and Conditions