Feasibility of low-dose CT with model-based iterative image reconstruction in follow-up of patients with testicular cancer Kevin P. Murphy, Lee Crush,

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Feasibility of low-dose CT with model-based iterative image reconstruction in follow-up of patients with testicular cancer Kevin P. Murphy, Lee Crush, Siobhan B. O’Neill, James Foody, Micheál Breen, Adrian Brady, Paul J. Kelly, Derek G. Power, Paul Sweeney, Jackie Bye, Owen J. O’Connor, Michael M. Maher, Kevin N. O’Regan European Journal of Radiology Open Volume 3, Pages 38-45 (January 2016) DOI: 10.1016/j.ejro.2016.01.002 Copyright © 2016 The Authors Terms and Conditions

Fig 1 Objective image noise assessment at the 8 assessed levels: right supraspinatus muscle at the level of the glenoid (level 1), erector spinae at the level of the carina (level 2), liver at diaphragm (level 3), liver at porta hepatis (level 4), right renal cortex at the renal hilum (level 5), erector spinae at level of the right kidney lower pole (level 6), psoas muscle at the iliac crest (level 7) and gluteus maximus at the level of the acetabular roof (level 8). European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 2 Objective signal-to-noise ratio (SNR) at the 8 assessed levels. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 3 Subjective image quality analysis. LD–MBIR images were significantly superior (p<0.001) for all recorded factors. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 4 Coronal CT images of the abdomen in a 36-year-old patient (BMI 20.7kg/m2) who underwent low-dose CT of the abdomen–pelvis (B) with estimated effective dose of 0.97mSv (ED). Mildly enlarged retroperitoneal nodes (arrows) are clearly seen on both CD–ASiR (A) and LD–MBIR (B) images. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 5 Axial CT images of the abdomen in a 47-year-old patient (BMI 28.6kg/m2) with an estimated effective dose (ED) of 3.1mSv for the low-dose thorax–abdomen–pelvis study (B). A mildly enlarged lymph node anterior to the abdominal aorta (arrows) is evident on both CD–ASiR (A) and LD–MBIR (B) studies. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 6 Axial CT images of the chest in a 36-year-old patient (BMI 21.0kg/m2) with an estimated effective dose of 1.86mSv ED for the low-dose thorax–abdomen–pelvis study (B). Subcentimetre pulmonary nodules (arrows) are clearly visible on both CD–ASiR (A) and LD–MBIR (B) datasets. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 7 Axial CT images from a 46-year-old study participant (BMI 31.3kg/m2) that had a low-dose abdominopelvic CT performed for an ED of 2.64mSv (B). Small hepatic cysts are visible on both CD–ASiR (A) and LD–MBIR (B) images. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 8 Zoomed up axial CT images from the patient in Fig. 7 shows CD–ASiR (A) and LD–MBIR (B) images of the liver cysts. European Journal of Radiology Open 2016 3, 38-45DOI: (10.1016/j.ejro.2016.01.002) Copyright © 2016 The Authors Terms and Conditions