Volume 13, Issue 4, Pages 217-225 (December 2006) Red cell morphology in leukemia, hypoplastic anemia and myelodysplastic syndrome  Durjoy Majumder, Debasis Banerjee, Sarmila Chandra, Subir Banerjee, Abhijit Chakrabarti  Pathophysiology  Volume 13, Issue 4, Pages 217-225 (December 2006) DOI: 10.1016/j.pathophys.2006.06.002 Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Scanning electron micrograph of the isolated red blood cells, with magnifications shown below each micrograph, from chronic myeloid leukemia (CML, A), acute myeloid leukemia (AML, B), chronic lymphocytic leukemia (CLL, C) and acute lymphoblastic leukemia (ALL, D). Pathophysiology 2006 13, 217-225DOI: (10.1016/j.pathophys.2006.06.002) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Scanning electron micrograph of the isolated red blood cells, with magnifications shown below each micrograph, from normal volunteers (normal, A), hypoplastic anemia (HPA, B) and myelodysplastic syndrome (MDS, C). Pathophysiology 2006 13, 217-225DOI: (10.1016/j.pathophys.2006.06.002) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Percentage of morphologically altered cells as detected by scanning electron micrograph of the red cell from healthy normal volunteers (NV), patients of hypoplastic anemia (HPA), myelodysplastic syndrome (MDS), chronic myeloid leukemia (CML), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia (ALL). Data presents as the mean and S.D. Bar shows the percentage of altered cells in the purified RBCs in different samples of a particular leukemia. Pathophysiology 2006 13, 217-225DOI: (10.1016/j.pathophys.2006.06.002) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Transmission electron micrograph of the red cell membranes, with magnifications shown below each micrograph, from normal volunteers (normal, A), from a patient of hypoplastic anemia (HPA, B), myelodysplastic syndrome (MDS) with refractory anemia (MDS-RA, C), MDS with myeloid blasts (MDS-AML, D), of chronic myeloid leukemia (CML, E), acute myeloid leukemia (AML, F), chronic lymphocytic leukemia (CLL, G) and acute lymphoblastic leukemia (ALL, H). Arrows indicate the pores in the cell membrane. Pathophysiology 2006 13, 217-225DOI: (10.1016/j.pathophys.2006.06.002) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Transmission electron micrograph of the red cell membranes, with magnifications shown below each micrograph, from normal volunteers (normal, A), from a patient of hypoplastic anemia (HPA, B), myelodysplastic syndrome (MDS) with refractory anemia (MDS-RA, C), MDS with myeloid blasts (MDS-AML, D), of chronic myeloid leukemia (CML, E), acute myeloid leukemia (AML, F), chronic lymphocytic leukemia (CLL, G) and acute lymphoblastic leukemia (ALL, H). Arrows indicate the pores in the cell membrane. Pathophysiology 2006 13, 217-225DOI: (10.1016/j.pathophys.2006.06.002) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions