Antiangiogenics meet nanotechnology

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Antiangiogenics meet nanotechnology Erkki Ruoslahti Cancer Cell Volume 2, Issue 2, Pages 97-98 (August 2002) DOI: 10.1016/S1535-6108(02)00100-9

Figure 1 Nanoparticles specifically target tumor vasculature Circulating nanoparticles bind to integrin on the endothelial cells of tumor vessels, but do not bind to the vessels in normal tissue. The bound particles discharge their DNA cargo into the cells. Thanks to Dr. Masanobu Komatsu for preparing the illustration. Cancer Cell 2002 2, 97-98DOI: (10.1016/S1535-6108(02)00100-9)