Proof-of-principle study of steam ablation as novel thermal therapy for saphenous varicose veins Renate R. van den Bos, MD, Rene Milleret, MD, Martino.

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Proof-of-principle study of steam ablation as novel thermal therapy for saphenous varicose veins Renate R. van den Bos, MD, Rene Milleret, MD, Martino Neumann, MD, PhD, Tamar Nijsten, MD, PhD Journal of Vascular Surgery Volume 53, Issue 1, Pages 181-186 (January 2011) DOI: 10.1016/j.jvs.2010.06.171 Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 1 Photographs show (A) the Steam Vein Sclerosis device, (B) the steam generator, and (C) the steam catheter. Journal of Vascular Surgery 2011 53, 181-186DOI: (10.1016/j.jvs.2010.06.171) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 2 Photomicrographs show a vein (A) immediately after treatment with steam ablation and (B) at 20 days after treatment with steam ablation (both hematoxylin-eosin stain, original magnification ×40). C, Detail (hematoxylin-eosin stain, original magnification ×200). D, Photomicrograph shows a vein 3 months after treatment with steam ablation (hematoxylin-eosin stain, original magnification ×40). Journal of Vascular Surgery 2011 53, 181-186DOI: (10.1016/j.jvs.2010.06.171) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 3 The positive, neutral, and negative impact of steam ablation is shown on the Venous Clinical Severity Score (VCSS), Aberdeen Varicose Vein Questionnaire (AVVQ), and the EuroQol quality-of-life questionnaire (EQ-5D) index and visual analog scale (VAS), four measures of clinical and health-related quality-of-life. Journal of Vascular Surgery 2011 53, 181-186DOI: (10.1016/j.jvs.2010.06.171) Copyright © 2011 Society for Vascular Surgery Terms and Conditions