Bilateral panuveitis in a child: a challenge

Slides:

Advertisements

Similar presentations

Mozhgan Rezaei Kanavi, MD. Ophthalmic Research Center Shahid Beheshti University of Medical Sciences, Tehran, Iran Appearance of Bilateral Corneal Opacities.

Advertisements

Cranial Nerve Clinical Correlations W. Rose 2011 Department of Kinesiology and Applied Physiology.

Grand Rounds Conference Reema Syed, MBBS University of Louisville Department of Ophthalmology and Visual Sciences August 7, 2015.

Bilateral Endogenous Bacterial Endophthalmitis and Bacteraemia as the presenting manifestation of Multiple Myeloma. Peter Cikatricis Peter Cikatricis 1,

Uveitic Macular Edema Nihal Elshakankiry, MD, PhD Professor of Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer of Ophthalmology Alexandria University.

Ocular Candidiasis Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom.

Behcet's Disease in an Indian Patient

Consultant, Uveitis Service

Cancer Associated Retinopathy

Assist. Lecturer of Ophthalmology

Chikungunya Retinitis

Tuberculosis Marco Coassin, Sylvia Marchi, Erika Mandarà, Valentina Mastrofilippo, Anna Maria Soldani and Luca Cimino Ocular Immunology.

Neuroretinitis secondary to Bartonella henselae

Unusual anterior Uveitis in a Child. Ocular History  10 year old boy  1/2001: OD>OS  red eyes  iris thickening,  endothelial precipitates, hyphema.

Debra Goldstein, MD Northwestern University Chicago, IL

Intraocular Tuberculosis

Posner-Schlossman Syndrome Bianka Sobolewska, MD Manfred Zierhut, MD Centre of Ophthalmology University of Tuebingen, Germany.

Diffuse infiltrating retinoblastoma > >. Ocular and General History  5 years old boy  Unremarkable birth history (BBW: 2800g, full-term)  No preceding.

Manfred Zierhut Centre of Ophthalmology University of Tuebingen, Germany Retinal Vasculitis.

ACUTE RETINAL NECROSIS

Whipple´s Disease Manfred Zierhut Centre of Ophthalmology

Panuveitis Mamta Agarwal Senior Consultant Uveitis & Cornea Services Sankara Nethralaya Chennai.

Central serous chorioretinopathy and uveitis Central serous chorioretinopathy and uveitis Rim Kahloun, MD Sonia Zaouali, MD Moncef Khairallah, MD Moncef.

Behçet´s Disease Christoph Deuter Centre for Ophthalmology, University Hospital, Tuebingen, Germany.

Centre of Ophthalmology University of Tuebingen, Germany

Manfred Zierhut Manfred Zierhut Centre of Ophthalmology University of Tuebingen, Germany Masquerade Syndrome.

A CASE OF INFECTIOUS AND AUTOIMMUNE DISEASE COEXISTENCE Elisabetta Miserocchi MD Department of Ophthalmology and Visual Sciences University Hospital San.

Choroidal Tuberculoma Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom.

Department of Cornea, Cataract & Refractive Surgery and *Ocular Microbiology Dr Rajendra Prasad Centre For Ophthalmic Sciences, AIIMS Dr. Manoj Sharma,

Sympathetic Ophthalmitis Annie Mathai, Rajeev K Reddy, Hemant S Trehan, Ritesh Narula Smt.Kanuri Santhamma Retina Vitreous Centre, Kallam Anji Reddy Campus,

Punctate Inner Choroidopathy Ahmed Magdy Bedda, MD, PhD Professor of Ophthalmology Rowayda M. Amin, MSc Assistant lecturer of Ophthalmology Alexandria.

Toxoplasmic Retinochoroiditis Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom.

Hypopyon Uveitis Linda Huang, MD Ronald Rescigno, MD Rutgers, New Jersey Medical School.

Cryptococcus neoformans Choroiditis Rupesh Agrawal, Ho Su Ling, Stephen Teoh Tan Tock Seng Hospital, National Healthcare Group Eye Institute, Singapore.

A Strange Case of Post-injection Uveitis Todd J. Purkiss, M.D., Ph.D. Retina Associates of Kentucky May 19, 2016.

OVERLAPPING FEATURES OF UNILATERAL VOGT-KOYANAGI-HARADA AND AMPPPE

Bilateral panuveitis in aN ELDERLY woman

Acute Retinal Necrosis

Acyclovir Resistant , VZV-ARN

HLA-B27 Associated Anterior Uveitis

HETEROCROMIC FUCHS UVEITIS ASSOCIATED to optic neuritis

Copyright © 2011 American Medical Association. All rights reserved.

Università degli Studi di Roma “La Sapienza”

Posner-Schlossman Syndrome

Sympathetic Ophthalmitis

Grand Rounds Conference Frozen Globe in a Newborn

Varicella-zoster necrotising retinitis with panuveitis following uncomplicated chickenpox in a seemingly immune competent child S Chamney1, J Yu1, S Hughes2,

Predictive Value of Quantitative PCR-Based Viral Burden Analysis for Eight Human Herpesviruses in Pediatric Solid Organ Transplant Patients Xin Bai,

First Presentation – OCT OS

Rickettsiosis Rim Kahloun, MD Bechir Jelliti, MD Salim Ben Yahia, MD

Behcet’s Syndrome N.Movaffagh MD Rheumatologist

Sympathetic ophthalmia

Consultant, Uveitis Service

HCUVA Murcia for Schistosome Choroiditis Juan Carlos Pastor Bernier

COXIELLA BURNETTI INFECTION AS POSSIBLE CAUSE OF PANUVEITIS

Anterior Uveitis in a Child

Predictive Value of Quantitative PCR-Based Viral Burden Analysis for Eight Human Herpesviruses in Pediatric Solid Organ Transplant Patients Xin Bai,

Sirolimus for acute pemphigus vulgaris: A case report and discussion of dualistic action providing for both immunosuppression and keratinocyte protection

National Institue of Infectious Diseases

Endogenous endophthalmitis associated to St. agalactiae

GRANULOMATOUS PANUVEITIS A LATE DIAGNOSIS OF S

Consultant, Uveitis Service

Follow up – After 11 Months July 2011

Consultant, Uveitis Service

Herpesviruses and the microbiome

Neuroretinitis Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital,

Unusual Uveitic CME Amir Hadayer, MD Ophthalmology & Visual Sciences

Uveitis Haneen Omar Abu Hani.

Eastern Ophthalmic Pathology Society 2018 Meeting Washington DC

Case Study Toolkit For general ophthalmologists and specialists treating non-anterior non-infectious uveitis Date of preparation: February 2019 | ALL-IMMU

Presentation transcript:

Bilateral panuveitis in a child: a challenge Soledad Rubio, MD. Luisa F. Giraldo, MD Lidia Cocho, MD. J.M. Herreras, MD, PhD.

7 07/30/2013 Consult: Bilateral posterior uveitis January 2013: Follicular conjunctivitis and Skin lesions Viral exanthema vs. Erythema multiforme (by biopsy). Dependent on oral Acyclovir January 2013: Anterior uveitis July 2013: BCVA RE: 20/30; LE: 20/20 IOP: 18 mmHg OU Slit lamp examination: cells in AC and vitreous (RE>LE)

Diagnostic PPV OD Weak positivity to EBV Famciclovir 750 mg daily Work-up: laboratories, serologies and chest X-ray: negative or normal, except HSV-1 IgG Bilateral panuveitis + HSV-1 IgG + Systemic rash responsive to Acyclovir Therapeutic trial with oral Acyclovir 2 g/daily  No clinical improvement after 2 weeks Diagnostic PPV OD Weak positivity to EBV Famciclovir 750 mg daily

11/26/2013 Pre-PPV Post-PPV

11/06/2014 Iris atrophy OD OS

11/26/2013 11/06/2014 Pre-PPV VA: OD = 0.8 OS = 1.0

Positive for Propionibacterium acnes intravitreal vancomycin x3 + 11/26/2013 11/06/2014 Positive for Propionibacterium acnes intravitreal vancomycin x3 + intravenous vancomycin

Antivirals and antibiotics failed in inducing remission 02/17/2015 Antivirals and antibiotics failed in inducing remission Immunosuppression with: Oral prednisone 1 mg/Kg Azathioprine 3 mg/Kg TRAPS TNFRSF1A gene mutation

Last visit 12/01/2016 BCVA OD: 20/200 OS: 20/25-2