Thomas A. Waldmann, Sigrid Dubois, Yutaka Tagaya Immunity

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Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes Thomas A. Waldmann, Sigrid Dubois, Yutaka Tagaya Immunity Volume 14, Issue 2, Pages 105-110 (February 2001) DOI: 10.1016/S1074-7613(01)00093-0

Figure 1 Diagrammatic Model Outlining the Distinct Roles Played by IL-2 and IL-15 in the Life and Death of T Cells IL-2 is required for AICD involved in peripheral tolerance to self-antigen whereas IL-15 inhibits this process. In addition, IL-15 supports whereas IL-2 inhibits the survival of memory phenotype CD8+ T cells Immunity 2001 14, 105-110DOI: (10.1016/S1074-7613(01)00093-0)