Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report  Cezmi A. Akdis, MD, Mübeccel Akdis, MD, PhD, Thomas Bieber, MD, PhD, Carsten Bindslev-Jensen, MD, Mark Boguniewicz, MD, Philippe Eigenmann, MD, Qutayba Hamid, MD, PhD, Alexander Kapp, MD, PhD, Donald Y.M. Leung, MD, PhD, Jasna Lipozencic, MD, PhD, Thomas A. Luger, MD, Antonella Muraro, MD, Natalija Novak, MD, Thomas A.E. Platts-Mills, MD, PhD, Lanny Rosenwasser, MD, Annika Scheynius, MD, PhD, F. Estelle R. Simons, MD, FRCPC, Jonathan Spergel, MD, PhD, Kristiina Turjanmaa, MD, PhD, Ulrich Wahn, MD, PhD, Stefan Weidinger, MD, Thomas Werfel, MD, Torsten Zuberbier, MD  Journal of Allergy and Clinical Immunology  Volume 118, Issue 1, Pages 152-169 (July 2006) DOI: 10.1016/j.jaci.2006.03.045 Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions

Fig 1 The natural history of AD from infancy to childhood obtained from the prospective birth cohort study Multicenter Atopy Study.3 Journal of Allergy and Clinical Immunology 2006 118, 152-169DOI: (10.1016/j.jaci.2006.03.045) Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions

Fig 2 Immunologic pathway involved in the progression of AD. Updated from Leung DY. Atopic dermatitis: new insights and opportunities for therapeutic intervention. J Allergy Clin Immunol 2000;105:860-76. LC, Langerhans cell; MC, mast cell; TSLP, human thymic stromal lymphopoietin; Ag, antigen; SAg, superantigen; AICD, activation-induced cell death; CLA, cutaneous lymphocyte antigen; MO, monocyte. Journal of Allergy and Clinical Immunology 2006 118, 152-169DOI: (10.1016/j.jaci.2006.03.045) Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions

Fig 3 Diagnostic approach to patients presenting with symptoms and signs of atopic dermatitis. Journal of Allergy and Clinical Immunology 2006 118, 152-169DOI: (10.1016/j.jaci.2006.03.045) Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions

Fig 4 Relative significance of complicating or exacerbating factors in patients with AD from infancy to adulthood. Journal of Allergy and Clinical Immunology 2006 118, 152-169DOI: (10.1016/j.jaci.2006.03.045) Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions

Fig 5 Stepwise management of patients with AD. Journal of Allergy and Clinical Immunology 2006 118, 152-169DOI: (10.1016/j.jaci.2006.03.045) Copyright © 2006 American Academy of Allergy, Asthma and Immunology and the European Academy of Allergology and Clinical Immunology Terms and Conditions