Statins and HIV:.

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Summary Prepared by Melvyn Rubenfire, MD
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Presentation transcript:

Statins and HIV:

Understanding the Changing CV Risk Burden in HIV Infection

Reasons for Increased ASCVD Risk in HIV Infection

Lipid Changes in HIV-Infected Individuals

Decline in MI in ART-Treated Individuals

SMART: Episodic vs Continuous ART

Assessment of CV Risk for Primary Prevention in HIV-Infected Individuals

Match Lipid Treatment to Level of Risk: Per NLA, Count Risk Factors, Add HIV as Additional Factor

ACC/AHA Lifestyle as the Foundation for ASCVD Risk-Reduction Efforts

Drug-Drug Interactions: Use of Statins With PIs

JUPITER: CV Benefits and Diabetes Risk

INTREPID: Pitavastatin vs Pravastatin in ART-Treated HIV-1-Infected Individuals With Dyslipidemia

INTREPID: Markers of Immune Activation and Arterial Inflammation

REPRIEVE: CV Outcomes Trial

Disparities in CV Care in the United States: HIV-Infected vs HIV-Uninfected Adults With CV Risk Factors

Challenges Associated With Statin Therapy in HIV-Infected Population

Other Anti-Inflammatory Strategies for HIV-Infected Individuals

Statin Therapy Considerations in HIV-Infected Individuals

Association Between LDL-C Lowering and CV Risk Reduction: Systematic Review and Meta-Analysis

Team-Based Care

Summary

Abbreviations

Abbreviations (cont)