Genotypic analysis of genes associated with transmission and drug resistance in the Beijing lineage of Mycobacterium tuberculosis  J-R. Chang, C-H. Lin,

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Genotypic analysis of genes associated with transmission and drug resistance in the Beijing lineage of Mycobacterium tuberculosis  J-R. Chang, C-H. Lin, S-F. Tsai, I-J. Su, F-C. Tseng, Y-T. Chen, T-S. Chiueh, J-R. Sun, T-S. Huang, Y-S. Chen, H-Y. Dou  Clinical Microbiology and Infection  Volume 17, Issue 9, Pages 1391-1396 (September 2011) DOI: 10.1111/j.1469-0691.2010.03436.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 A minimum spanning tree based on 24-MIRU-VNTR genotyping of 338 Mycobacterium tuberculosis Beijing isolates. The circles represent different types classified by 24-MIRU-VNTR genotypes and were coloured according to the ST classification described in the text. The sizes of circles represent the number of isolates with a particular genotype. Clinical Microbiology and Infection 2011 17, 1391-1396DOI: (10.1111/j.1469-0691.2010.03436.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Scheme of the proposed evolution of Beijing lineages. The scheme is based on the deletion of genomic regions (RD, region of difference, shown in grey rectangles), the NTF region with IS6110 insertions, and types of sequence designations from the studies of Filliol et al. [5] and Iwamoto et al. [14]. Clinical Microbiology and Infection 2011 17, 1391-1396DOI: (10.1111/j.1469-0691.2010.03436.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions