Atypical lymphocytic reaction with epidermotropism and lymphocytic vasculopathic reaction (lymphocytic vasculitis) after treatment with imiquimod Jesús.

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Atypical lymphocytic reaction with epidermotropism and lymphocytic vasculopathic reaction (lymphocytic vasculitis) after treatment with imiquimod Jesús Treviño, Victor G. Prieto, MD, PhD, Ronald Hearne, MD, Aaron Polk, MD, A. Hafeez Diwan, MD, PhD Journal of the American Academy of Dermatology Volume 55, Issue 5, Pages S123-S125 (November 2006) DOI: 10.1016/j.jaad.2006.01.070 Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Dense lymphoid infiltrate with epidermotropism (A and B) and infiltration of vessel walls in dermis (C). (Hematoxylin-eosin stain; original magnifications: A, ×100; B and C, ×200.) Journal of the American Academy of Dermatology 2006 55, S123-S125DOI: (10.1016/j.jaad.2006.01.070) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Most lymphocytes express CD4 (anti-CD4, AEC). B, Less than 30% of lymphocytes express CD8 (anti-CD8, AEC). C, Scattered clusters of CD20 lymphocytes are also seen (anti-CD20, AEC). Journal of the American Academy of Dermatology 2006 55, S123-S125DOI: (10.1016/j.jaad.2006.01.070) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions