Melanoma in skin affected with keratoderma palmoplantaris hereditaria (Mal de Meleda): Treatment with excision and grafting Leonardo Sartore, MD, Matteo Bordignon, MD, Franco Bassetto, MD, PhD, Anna Voltan, MD, Valeria Tomat, MD, Mauro Alaibac, MD, PhD Journal of the American Academy of Dermatology Volume 61, Issue 1, Pages 161-163 (July 2009) DOI: 10.1016/j.jaad.2009.01.007 Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions
Fig 1 A, Large mass on the dorsal surface of the left hand. Note the tumor located within the skin area affected by Mal de Meleda. B, Result of the skin autograft after the excision of the mass. Note the absence of hyperkeratosis in the graft. Journal of the American Academy of Dermatology 2009 61, 161-163DOI: (10.1016/j.jaad.2009.01.007) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions
Fig 2 Hyperkeratosis and proliferation of atypical melanocytes involving both epidermal and dermal compartments. (Hematoxylin-eosin stain; original magnification: ×40.) Journal of the American Academy of Dermatology 2009 61, 161-163DOI: (10.1016/j.jaad.2009.01.007) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions