The effects of i.v. fentanyl administration on the minimum alveolar concentration of isoflurane in horses  Thomasy S.M. , Steffey E.P. , Mama K.R. , Solano.

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The effects of i.v. fentanyl administration on the minimum alveolar concentration of isoflurane in horses  Thomasy S.M. , Steffey E.P. , Mama K.R. , Solano A , Stanley S.D.   British Journal of Anaesthesia  Volume 97, Issue 2, Pages 232-237 (August 2006) DOI: 10.1093/bja/ael116 Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 1 Mean (+sd) plasma fentanyl concentration vs time after a loading dose administered over 12 min, then a CRI to target three different fentanyl concentrations in eight horses (n=4–6 at each data point). British Journal of Anaesthesia 2006 97, 232-237DOI: (10.1093/bja/ael116) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 2 Isoflurane MAC at different plasma fentanyl concentrations in eight horses. British Journal of Anaesthesia 2006 97, 232-237DOI: (10.1093/bja/ael116) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 3 Percentage reduction in isoflurane MAC [mean (sd)] at three different plasma fentanyl concentrations in eight horses. *P<0.05 from baseline. British Journal of Anaesthesia 2006 97, 232-237DOI: (10.1093/bja/ael116) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 4 Mean (+sd) HR (a) and MAP (b) in eight isoflurane-anaesthetized horses immediately before and after noxious stimulation at fentanyl concentrations (FC) of 0, 0.72, 8.43 and 13.31 ng ml−1. aP<0.05 from 0 FC. bP<0.05 from 0.72 FC. cP<0.05 from 8.43 FC. *P<0.05 from pre-noxious stimulation. British Journal of Anaesthesia 2006 97, 232-237DOI: (10.1093/bja/ael116) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

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