Sugar Codes for Axons? Neuron

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Presentation transcript:

Sugar Codes for Axons? Neuron Christine E. Holt, Barry J. Dickson Neuron Volume 46, Issue 2, Pages 169-172 (April 2005) DOI: 10.1016/j.neuron.2005.03.021 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 Generation of Sequence Diversity in Heparan Sulfate Chain Biosynthesis The first step in HS biosynthesis involves the creation of a tetrasaccharide linkage region to a serine in the core protein (not shown). The addition of N-acetylglucosamine (GlcNAc) then commits the chain to the HS synthesis pathway. See text for further details. GlcA, glucuronic acid; IdoA, iduronic acid; GlcNS, N-sulfated glucosamine. (After Turnbull et al., 2001). Neuron 2005 46, 169-172DOI: (10.1016/j.neuron.2005.03.021) Copyright © 2005 Elsevier Inc. Terms and Conditions