Trial analysis results comparing ACE inhibitors/ARBs with other antihypertensive drugs on renal disease progression End point Relative risk (95% CI) p Doubling of creatinine 0.71 (0.49-1.04) 0.07 End-stage renal disease 0.87 (0.75-0.99) 0.04 Casas JP et al. Lancet 2005; 366: 2026-2033
Trial analysis results comparing ACE inhibitors/ARBs with other antihypertensive drugs in diabetic nephropathy End point Relative risk (95% CI) Doubling of creatinine 1.09 (0.55-2.15) End-stage renal disease 0.89 (0.74-1.07) Casas JP et al. Lancet 2005; 366: 2026-2033