The origin of cancer stem cells

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Presentation transcript:

The origin of cancer stem cells Hien T. Dang, Anuradha Budhu, Xin W. Wang Journal of Hepatology Volume 60, Issue 6, Pages 1304-1305 (June 2014) DOI: 10.1016/j.jhep.2014.03.001 Copyright © 2014 Terms and Conditions

Fig. 1 The impact of the liver milieu on preneoplastic lesions. Within the cirrhotic liver are foci of altered hepatocytes (FAH) that harbors multiple hepatic cell lineages including aggregates of hepatic cancer progenitor cells (HcPCs). The damaged liver provides a microenvironment that is conducive for tumor progression, which allows HcPCs to become cancer stem cells (CSCs). Journal of Hepatology 2014 60, 1304-1305DOI: (10.1016/j.jhep.2014.03.001) Copyright © 2014 Terms and Conditions