The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized Trial  Gautam S. Ghatnekar, Christina L. Grek, David G. Armstrong, Sanjay C. Desai, Robert G. Gourdie  Journal of Investigative Dermatology  Volume 135, Issue 1, Pages 289-298 (January 2015) DOI: 10.1038/jid.2014.318 Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 CONSORT flow diagram of participants. ITT, intent-to-treat; PP, per protocol; SOC, standard of care. Journal of Investigative Dermatology 2015 135, 289-298DOI: (10.1038/jid.2014.318) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Kaplan–Meier plot of time to 100% ulcer closure with ACT1 and standard of care (SOC) compared with standard of care alone. (a) Intent-to-treat (ITT) population. (b) Per protocol (PP) population. Journal of Investigative Dermatology 2015 135, 289-298DOI: (10.1038/jid.2014.318) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions