Whole-exome sequencing reveals differences between nail apparatus melanoma and acral melanoma Minho Lee, PhD, Jonghwan Yoon, BS, Yeun-Jun Chung, MD, PhD, Soo Young Lee, MD, Jin Young Choi, MD, Ok Ran Shin, MD, PhD, Ho Youn Park, MD, Won-Jong Bahk, MD, PhD, Dong Soo Yu, MD, PhD, Young Bok Lee, MD, PhD Journal of the American Academy of Dermatology Volume 79, Issue 3, Pages 559-561.e1 (September 2018) DOI: 10.1016/j.jaad.2018.02.019 Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions
Fig 1 Cancer-related somatic mutations and copy number alterations identified in AM and NAM. Gene mutations were identified by COSMIC. COSMIC top 20 genes in malignant melanoma (red lettering), somatic mutations (black dots), copy number gains (blue bocks), and copy number losses (red blocks) are indicated. AM, Acral melanoma; COSMIC, Catalogue of Somatic Mutations in Cancer; NAM, nail apparatus melanoma; SNV, single-nucleotide variant. Journal of the American Academy of Dermatology 2018 79, 559-561.e1DOI: (10.1016/j.jaad.2018.02.019) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions