Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2016.122 Figure 3 Most frequent somatic mutations in patients with multiple myeloma Figure 3 | Most frequent somatic mutations in patients with multiple myeloma. Mutation frequencies were calculated by averaging the data from three whole-exome sequencing studies comprising a total of 733 patients6,7,9. MM, multiple myeloma; WES, whole-exome sequencing. Manier, S. et al. (2016) Genomic complexity of multiple myeloma and its clinical implications Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2016.122