Naïve and central memory T-cell lymphopenia in end-stage renal disease

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Naïve and central memory T-cell lymphopenia in end-stage renal disease J.-W. Yoon, S. Gollapudi, M.V. Pahl, N.D. Vaziri Kidney International Volume 70, Issue 2, Pages 371-376 (July 2006) DOI: 10.1038/sj.ki.5001550 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 A linear model of central and effector T-cell memory generation in primary response to infection. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Distribution of CD4+ and CD8+ T cells in control and ESRD groups. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 3 Distribution of naïve, CM, TEM, and TEMRA subpopulations of CD4+ T lymphocytes in the control and ESRD groups. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 4 Distribution of naïve, CM, TEM, and TEMRA subpopulations of CD8+ T lymphocytes in the control and ESRD groups. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 5 Distribution of CD4+ and CD8+ T cells in diabetic (DM, n=12) and non-diabetic (n=9) ESRD patients. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 6 Distribution of naïve, CM, TEM, and TEMRA subpopulations of CD8+ T lymphocytes in diabetic (DM) and non-diabetic ESRD patients. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 7 Effect of hemodialysis on naïve, CM, TEM, and TEMRA subpopulations of CD8+ T lymphocytes. *P<0.05 vs pre-dialysis. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 8 Homing receptor (CCR7)-positive T-cell apoptosis, assessed by Annexin V staining in ESRD and control groups. *P<0.05. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 9 Correlations between serum concentrations of urea nitrogen, creatinine, MDA, and phosphorous with the number of CD4+ naïve T lymphocytes in ESRD and control groups. Kidney International 2006 70, 371-376DOI: (10.1038/sj.ki.5001550) Copyright © 2006 International Society of Nephrology Terms and Conditions