Graphs to show the effects of Inhibitors on Enzyme Action

Slides:



Advertisements
Similar presentations
Enzyme Activity The properties of enzymes related to their tertiary structure.The effects of change in temperature,pH,substrate concentration,and competitive.
Advertisements

Free Response Questions
Types of inhibition In competitive inhibition a molecule very close in shape to the true substrate competes for the active site of the enzyme. This means.
8.1 Metabolism Applications: Understanding:
 Definition of metabolism  Definition of a substrate  Characteristics of metabolic pathways  Why we need metabolic pathways.
NZYMES NZY MES. Amylase catalyses the breakdown of starch AmylaseStarchAmylaseMaltose Enzyme Substrate EnzymeProduct.
Slide 1 of 50 Enzymes  Enzymes are biological catalysts  Proteins  Catalyst  Lower activation energy  Increases the rate of the reaction  Affects.
WJEC GCE BIOLOGY Inhibitors and Enzyme Action S TATION 2 G RAPHS TO SHOW THE EFFECTS OF I NHIBITORS ON E NZYME A CTION N AVIGATE YOUR WAY THOUGH ALL OF.
Enzymes Proteins Act as catalysts to speed up chemical reactions Are specific – each enzyme can carry out only one type of reaction. Animation of Enzyme.
ENZYMES. Enzymes are proteins that act on a substance called a substrate. enzyme substrate > product In the above reaction the enzyme's active.
 I can describe the structure and explain the significance and functions of enzymes in biological systems › I can describe why an investment of activation.
WJEC GCE BIOLOGY Inhibitors and Enzyme Action Graphs to show the effects of Inhibitors on Enzyme Action 3.2.
Enzymes.  Proteins play major roles in the cell, but none as important as making up enzymes.  Enzymes permit reactions to occur at rates of thousands.
7.6 Enzymes (AHL) Pp Pp
Competitive & Non-Competitive
Cell processes (e.g. respiration or photosynthesis) consist of series of pathways controlled by enzymes ABCDEFABCDEF Enzyme pathways eFeF eDeD eCeC eAeA.
Enzymes Catalyze (speed up) reactions Recognize and bind specific substrates Act repeatedly Most are proteins Reaction does not alter them.
A Lock-and-Key Enzyme Animation. Enzyme Substrate Active Site.
Enzyme Action. What you should learn How biochemical reactions are catalysed by enzymes. The precise role of active sites. Types of enzyme inhibition.
Chapter 20 Enzymes and Vitamins
Competitive, Non- competitive, & End- product inhibition by allosteric sites.
Lock and Key Model Enzymes are specific to their substrates Substrate and active site match each other in two ways: Structurally  substrates that don’t.
Themes: Structure meets Function
Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
ENZYMES & ENERGY ACADEMIC BIOLOGY. __________________________________________________________________________________________________________________________________________________.
Chapter 8.1, 8.2, 8.4, 8.5.  metabolism is the process of breaking down and creating molecules necessary for life ◦ each step in this process is driven.
Enzymes. Enzymes are… Proteins that act as catalysts (accelerate reactions) by creating a new reaction pathway Are specific for what they catalyze and.
Enzymes. What is an enzyme? Organic catalyst Protein molecule.
Enzyme Regulation Chapter Biochemical Pathways Regulations of Enzymes Objective: I can identify and describe the different ways enzymes are regulated,
8.2.  Chemical reactions are continually occurring in our bodies to keep us alive.  These chemical reactions must occur at low temperatures so that.
Chapter 5: Cellular Processes Pg. 85 Enzyme Regulation Objective: I can identify and describe the different ways enzymes are regulated, based.
Lesson 5 Enzymes. Catalyst: something that increases the rate of reactions Enzymes are biological catalysts Often ends with –ase Most enzymes are proteins.
Enzymes Chapter 8.
Enzyme Cofactors Some enzymes require cofactors to be active.
Who Wants To Be A Millionaire?
Metabolic Pathways (e)
Unit Metabolic Pathways & their Control
Enzymes.
Control of Metabolic Pathways (2)
What is an enzyme? Enzymes are proteins, which means they are organic.
Chemical Reactions and Enzymes
Objective: I can explain how enzymes work and what environmental factors affect them. Agenda Bell Ringer Notes over enzymes Enzyme lab.
ENZYME INHIBITION.
Enzymes.
Enzymes.
Ch 6 Section 2 Enzymes.
Enzymes.
Enzymes.
8.1 Metabolism Essential idea: Metabolic reactions are regulated in response to the cell’s needs.
Factors affecting Enzymes
What are Enzymes? Catalysts change the rate of the reaction without being altered themselves. Enzymes are biological catalysts. Enzymes are (mostly) proteins,
Practice Exam Questions – PEER ASSESS
TSW identify the structure and function of an enzyme
Do Now How would you improve the answer to the question below?
Enzymes.
Enzymes.
Changing substrate concentration
Enzymes.
Enzymes.
Enzyme Regulation 1.
C. Some factors are: 1. pH 2. Temperature
Enzymes Biological catalyst – it speeds up reactions without being permanently changed.
ENZYME Enzyme Reaction Energy of reaction Factors affect rate Other.
Do Now Take out your: Vocabulary notes + Toothpickase lab
2.5 - Enzymes.
8.1 Metabolism Understanding:
Enzymes.
SBI 4U: Metablic Processes
Presentation transcript:

Graphs to show the effects of Inhibitors on Enzyme Action

Rate of reaction 1 Substrate concentration

Forward Explanation

2 Rate of reaction 1 Substrate concentration

Forward Every active site is saturated. The rate of the reaction is at its highest. Close Explanation

3 2 Rate of reaction 1 Substrate concentration

Forward Every active site is saturated, so there is no increase in the rate of reaction. Close Example

3 2 Revise 1 Competitive Inhibitor Rate of reaction Substrate concentration

2 Revise 1 Non-competitive Inhibitor Rate of reaction Substrate concentration

Forward A competitive inhibitor binds to the enzyme’s active site, and slows down the process. Close Explanation

Forward The substrate will soon find an active site. The effect of a competitive inhibitor is to slow down the process. Close Explanation

2 Rate of reaction Revise 1 Substrate concentration

Forward The shape of the active site changes because the non-competitive inhibitor has bound to an allosteric site; so preventing an enzyme-substrate complex from forming. Close Explanation

Forward The reaction rate cannot reach the same point because the non-competitive inhibitors have changed the shape of some of the active sites. Close Explanation