Mitral Valve Disease

This program will include a discussion of off-label treatment with devices not approved by the FDA for use in the US.

Mitral Valve Disease Overview

Increasing Prevalence of Valvular Heart Disease in the Elderly

Prevalence of Mitral Regurgitation in US

MVD Is an Extremely Common Disease With a Massive Prevalence-Treatment Gap

Practice Gaps Among PCPs, Cardiologists, and Cardiac Surgeons

Components of MR Assessment

Mitral Regurgitation Etiologies

Approach to MR Assessment

When to Refer?*

Chronic Severe Primary MR

CTSNet Trial 2-Year Outcomes

CTSNet Trial 2-Year Outcomes (cont)

COAPT Trial Design

MR in Asymptomatic Patients

Active Surveillance in Asymptomatic Patients

Stages of Secondary MR

Chronic Severe Secondary MR

Mitral Valve Anatomic “Sweet Spots”

Implantation Process

Left Heart Disease

Shared Decision Making Favoring Mechanical Prosthesis or Bioprosthesis

Early Experience With TMVR

Apollo TMVR Trial

Apollo TMVR Trial Study Endpoints

Indications for Surgery for MR

Conclusion

Abbreviations

Abbreviations (cont)

Abbreviations (cont)