Epigenomics of Retinal Development in Mice and Humans

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Epigenomics of Retinal Development in Mice and Humans Nicolas Lonfat, Connie Cepko Neuron Volume 94, Issue 3, Pages 420-423 (May 2017) DOI: 10.1016/j.neuron.2017.04.029 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Dynamics of Retinal Epigenomes and Transcriptomes during Development and Disease Aldiri et al., (2017) characterized the transcriptional and epigenetic changes that occur during development of the retina in mice and humans. They also profiled the epigenomes of iPSCs derived from the retina and those from retinoblastoma cells. Chromatin architecture was analyzed at different stages of development, at different scales, focusing on the organization of histone marks and DNA methylation, interactions among genes in the context of TADs, and analysis of the overall nuclear structure within rods. Neuron 2017 94, 420-423DOI: (10.1016/j.neuron.2017.04.029) Copyright © 2017 Elsevier Inc. Terms and Conditions