Marc P. Scherer, Anthony W. Gummer Biophysical Journal

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Presentation transcript:

How Many States Can the Motor Molecule, Prestin, Assume in an Electric Field? Marc P. Scherer, Anthony W. Gummer Biophysical Journal Volume 88, Issue 5, Pages L27-L29 (May 2005) DOI: 10.1529/biophysj.105.059782 Copyright © 2005 The Biophysical Society Terms and Conditions

Figure 1 The symbols show a set of data artificially generated by adding 1% uniformly distributed random error to a Brillouin function (Eq. 1) with J=∞; that is, the data represent a classical dipole. E is proportional to transmembrane voltage. Fitted to the data is the scaled Brillouin function (Eq. 4) with J=1/2 (two states, QM=0.873±0.007, ɛ=0.350±0.009), J=2 (five states, QM=0.897±0.005, ɛ=0.724±0.015), and J=∞ (classical limit, QM=0.996±0.006, ɛ=1.021±0.020). Obviously, the fitted lines are almost indistinguishable. Biophysical Journal 2005 88, L27-L29DOI: (10.1529/biophysj.105.059782) Copyright © 2005 The Biophysical Society Terms and Conditions